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Thymosin Alpha 1

Thymosin Alpha 1

Thymosin alpha 1 is a 28 amino acid peptide endogenously produced by the thymus.1 Prior research shows that it stimulates the adaptive immune response via its action as a toll-like receptor (TLR)-9 and TLR-2 agonist in antigen-presenting immune cells.1,2 Thymosin alpha 1 also stimulates the production of T-cell dependent antibodies as well as cytokine-mediated inflammation.1 Its various effects on immune cells hold promise for future research.

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Please note that all products available on our website are supplied in lyophilized powder form and typically require reconstitution. Reconstitution involves adding a suitable solvent to achieve the desired concentration for your experiments. We do not provide any instructions or advise on any research protocols.

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In Stock Batch COAs:

Sold Out Batch COAs for Reference:

12.06mg Batch Test Results: TA1-0001 (Click here)
10.96mg Batch Test Results: TA1-0002 (Click here)

Thymosin alpha 1 is a 28 amino acid peptide initially isolated from bovine thymuses in the 1970s.1 Since then, research has shown its various effects on immune cells and responses.1,2 It is endogenously produced and acts to regulate both the innate and adaptive immune systems.1,2

Much of thymosin alpha 1’s immune action is due to its effects on T-cells2 — it increases T-cell differentiation and maturation, the activity of dendritic and natural killer cells, as well as cytokine-mediated inflammation.1 Thus, not only does it activate natural killer cells, it also increases maturation of T-cells into CD4+/CD8+ T-cells,1 strengthening the immune response on multiple fronts.

Thymosin alpha 1 also functions in antigen-presenting cells as an agonist to toll-like receptor (TLR)-9 and TLR-2, which serves to stimulate the adaptive and humoral immune responses.1,2 It’s various immune-modulating functions make thymosin alpha 1 a promising candidate for future research.

Research Studies:

  1. Dominari A, Hathaway Iii D, Pandav K, et al. Thymosin alpha 1: A comprehensive review of the literature. World J Virol. 2020;9(5):67-78. doi: 10.5501/wjv.v9.i5.67
  2.  
  3. Garaci E. From thymus to cystic fibrosis: the amazing life of thymosin alpha 1. Expert Opin Biol Ther. 2018;18(sup1):9-11. doi: 10.1080/14712598.2018.1484447
Sequence: Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH
Molecular Formula: C129H215N33O55
Molecular Weight: 3108.3 g/mol
PubChem CID: 16130571
CAS Number: 62304-98-7

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What is BPC - 157 (generic for BPC - 157®)?

Peptides are short chains of amino acids, the building blocks of proteins, that play essential roles in various biological processes. We offer a range of peptides specifically designed to address different health concerns, such as weight loss, inflammation, and overall wellness. These peptides work by targeting specific areas in the body, promoting various beneficial effects.

What is BPC - 157 (generic for BPC - 157®)?

Peptides are short chains of amino acids, the building blocks of proteins, that play essential roles in various biological processes. We offer a range of peptides specifically designed to address different health concerns, such as weight loss, inflammation, and overall wellness. These peptides work by targeting specific areas in the body, promoting various beneficial effects.

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Peptides are short chains of amino acids, the building blocks of proteins, that play essential roles in various biological processes. We offer a range of peptides specifically designed to address different health concerns, such as weight loss, inflammation, and overall wellness.

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