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Kisspeptin-10

Kisspeptin-10

Kisspeptin-10 is a powerful binding agent for the kisspeptin receptor [often termed KISS1R or G-protein coupled receptor 54 (GPR54)].1,2 It is a member of the kisspeptin family of peptides, which are derived from the KISS1 gene and share many similarities.2 The kisspeptin system is primarily known for its key role in regulating reproduction3 — as it stimulates neurons to release gonadotrophin hormone-releasing hormone (GnRH)1 — but requires further investigation into its potential roles in nutrition, fertility, cancer metastasis, kidney development, and more.

This product is a lyophilized powder with mannitol filler in a 3mL glass vial.

Pricing & COAs:

  • 3.85mg: $35.99 per vialBatch Test Results: KISS-0001 (Click here)

Please note that all products available on our website are supplied in lyophilized powder form and typically require reconstitution. Reconstitution involves adding a suitable solvent to achieve the desired concentration for your experiments. We do not provide any instructions or advise on any research protocols.

This product is currently out of stock and unavailable.

Kisspeptin-10 is a potent endogenous ligand for the kisspeptin receptor, commonly referred to as KISS1R or G-protein coupled receptor 54 (GPR54).1,2 Kisspeptin, via its receptor, stimulates hypothalamic gonadotrophin releasing-hormone (GnRH) release, playing a critical role in the regulation of reproduction.1,3

Initially discovered in 1996 as a metastasis inhibitor,1,2 kisspeptin has been found to be expressed in the placenta, testis, ovaries, pancreas, and small intestines.1,4 In addition to being essential for reproduction, studies suggest kisspeptin plays a role in the pathway between nutrition and reproduction.1 The kisspeptin system is involved in a slew of physiological processes, with research suggesting it may play roles in kidney development, breast cancer metastasis, and more.4

Research Studies:

  1. Clarke H, Dhillo WS, Jayasena CN. Comprehensive review on kisspeptin and its role in reproductive disorders. Endocrinol Metab. 2015;30(2):142-141. doi: 10.3803/EnM.2015.30.2.124
  2.  
  3. Szydełko-Gorzkowicz M, Poniedziałek-Czajkowska E, Mierzyński R, Sotowski M, Leszczyńska-Gorzelak B. The role of kisspeptin in the pathogenesis of pregnancy complications: a narrative review. Int J Mol Sci. 2022;23(12):6611. Published 2022 Jun 14. doi: 10.3390/ijms23126611
  4.  
  5. Kanda S, Oka Y. Kisspeptin. In: Ando H, Ukena K, Nagata S, eds. Handbook of Hormones: Comparative Endocrinology for Basic and Clinical Research. 2nd ed. Elsevier; 2021:21-23.
  6.  
  7. Bhattacharya M, Babywa AV. Kisspeptin: beyond the brain. Endocrinol. 2015;156(4):1218-1227. doi: 10.1210/en.2014-1915
Sequence: H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
Molecular Formula: C63H83N17O14
Molecular Weight: 1302.4 g/mol
PubChem CID: 25240297
CAS Number: 374675-21-5

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BPC-157 Vial

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What is BPC - 157 (generic for BPC - 157®)?

Peptides are short chains of amino acids, the building blocks of proteins, that play essential roles in various biological processes. We offer a range of peptides specifically designed to address different health concerns, such as weight loss, inflammation, and overall wellness. These peptides work by targeting specific areas in the body, promoting various beneficial effects.

What is BPC - 157 (generic for BPC - 157®)?

Peptides are short chains of amino acids, the building blocks of proteins, that play essential roles in various biological processes. We offer a range of peptides specifically designed to address different health concerns, such as weight loss, inflammation, and overall wellness. These peptides work by targeting specific areas in the body, promoting various beneficial effects.

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Peptides are short chains of amino acids, the building blocks of proteins, that play essential roles in various biological processes. We offer a range of peptides specifically designed to address different health concerns, such as weight loss, inflammation, and overall wellness.

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