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CJC-1295 with DAC

CJC-1295 with DAC

CJC-1295 with DAC is a synthetic analog of growth hormone-releasing hormone (GHRH).1-3 As an analog and agonist of GHRH, CJC-1295 without DAC stimulates the production and secretion of growth hormone4 which may affect many physiological systems and processes including the immune system, gametogenesis, and more.5 The addition of the drug affinity complex (DAC) increases the half-life when compared to endogenous GHRH and CJC-1295 without DAC.2,3

 

Please see below for previous batch COAs.
 

Please note that all products available on our website are supplied in lyophilized powder form and typically require reconstitution. Reconstitution involves adding a suitable solvent to achieve the desired concentration for your experiments. We do not provide any instructions or advise on any research protocols.

This product is currently out of stock and unavailable.

In Stock Batch COAs:

Sold Out Batch COAs for Reference:

5.06mg Batch Test Results: DAC-0001 (Click here)
5.65mg Batch Test Results: DAC-0002 (Click here)
CJC-1295 with DAC is a synthetic peptide agonist of growth hormone-releasing hormone (GHRH).1-3 GHRH is known to stimulate the production and secretion of growth hormone (GH),4 which plays a part in a variety of physiological processes.5 Research suggestsw CJC-1295 with DAC stimulates an increase in GH and insulin-like growth factor (IGF)-1.2,3

CJC-1295 with DAC is a tetrasubstituted form of growth hormone-releasing factor (GRF),1,3 with the four amino acid substitutions improving the compound’s resistance to degradation.3 In addition, CJC-1295 with DAC includes a drug affinity complex (DAC) which allows the compound to bind to serum albumin, lending it an increased half-life compared to endogenous GHRH and CJC-1295 without DAC.2,3

Research Studies:

  1. Jetté L, Léger R, Thibaudeau K, et al. Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog. Endocrinology. 2005;146(7):3052-3058. doi: 10.1210/en.2004-1286
  2.  
  3. Sackmann-Sala L, Ding J, Frohman LA, Kopchick JJ. Activation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects. Growth Horm IGF Res. 2009;19(6):471-477. doi: 10.1016/j.ghir.2009.03.001
  4.  
  5. Teichman SL, Neale A, Lawrence B, et al. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. 2006;91(3):799-805. doi: 10.1210/jc.2005-1536
  6.  
  7. Tachibana T. Growth hormone-releasing hormone. In: Ando H, Ukena K, Nagata S, eds. Handbook of Hormones: Comparative Endocrinology for Basic and Clinical Research. 2nd ed. Elsevier; 2021:255-257.
  8.  
  9. Moriyama S. Growth hormone. In: Ando H, Ukena K, Nagata S, eds. Handbook of Hormones: Comparative Endocrinology for Basic and Clinical Research. 2nd ed. Elsevier; 2021:199-201.
Sequence: H-Tyr-Asp-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys(maleimido)-NH2
Molecular Formula: C165H269N47O46
Molecular Weight: 3647 g/mol
PubChem CID: 91971820
CAS Number: 446262-90-4

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Peptides are short chains of amino acids, the building blocks of proteins, that play essential roles in various biological processes. We offer a range of peptides specifically designed to address different health concerns, such as weight loss, inflammation, and overall wellness. These peptides work by targeting specific areas in the body, promoting various beneficial effects.

What is BPC - 157 (generic for BPC - 157®)?

Peptides are short chains of amino acids, the building blocks of proteins, that play essential roles in various biological processes. We offer a range of peptides specifically designed to address different health concerns, such as weight loss, inflammation, and overall wellness. These peptides work by targeting specific areas in the body, promoting various beneficial effects.

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