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Cagrilintide-without-MG

Cagrilintide

Cagrilintide is a long-acting, non-selective amylin analogue1-3 currently at the forefront of peptide research. Improving upon prior amylin analogues like pramlintide, it was developed to have an extended half-life while also preventing amylin protein aggregation.1-3

See below for previous batch COAs.

Please note that all products available on our website are supplied in lyophilized powder form and typically require reconstitution. Reconstitution involves adding a suitable solvent to achieve the desired concentration for your experiments. We do not provide any instructions or advise on any research protocols.

This product is currently out of stock and unavailable.

In Stock Batch COAs:

Sold Out Batch COAs for Reference:

7.92mg Batch Test Results: HCAG-0001 (Click here)
6.29mg Batch Test Results: HCAG-0003 (Click here)

Amylin is a 37 amino acid peptide primarily produced by pancreatic beta cells.1-3 It is secreted along with insulin, and the similarities between the two render the synthesis and excretion similar.1-3 Amylin has been shown to have effects in a variety of tissues — not only the stomach and pancreas, but also the central nervous and cardiovascular systems.2,3

Cagrilintide was developed to build upon the experiences of the first amylin analogue — pramlintide.1,2 While pramlintide did exhibit efficacy and desired activity, its short half-life and undesirable side effect profile left much room for improvement.1,2 Cagrilintide has a number of chemical alterations to enhance its potency, stability, and half-life, including a similar albumin-binding mechanism as semaglutide.1,2 As a relatively newly developed peptide, the research possibilities with cagrilintide are vast.

Research Studies:

  1. Kruse T, Hansen JL, Dahl K, et al. Development of cagrilintide, a long-acting amylin analogue. J Med Chem. 2021;64(15):11183-11194. doi: 10.1021/acs.jmedchem.1c00565
  2.  
  3. D’Ascanio AM, Mullaly JA, Firshman WH. Cagrilintide: A long-acting amylin analog for the treatment of obesity. Cardiol Rev. 2024;32(1):83-90. doi: 10.1097/CRD.0000000000000513
  4.  
  5. Eržen S, Tonin G, Jurišić Eržen D, Klen J. Amylin, another important neuroendocrine hormone for the treatment of obesity. Int J Mol Sci. 2024;25:1417. doi: 10.3390/ijms25031517
  6.  
Sequence: Unk-γGlu-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Glu-Phe-Leu-Arg-His-Ser-Ser-Asn-DAsn-Phe-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Pro-NH2
Molecular Formula: C194H312N54O59S2
Molecular Weight: 4409 g/mol
PubChem CID: 167312356
CAS Number: 1415456-99-3

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BPC-157 Vial

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What is BPC - 157 (generic for BPC - 157®)?

Peptides are short chains of amino acids, the building blocks of proteins, that play essential roles in various biological processes. We offer a range of peptides specifically designed to address different health concerns, such as weight loss, inflammation, and overall wellness. These peptides work by targeting specific areas in the body, promoting various beneficial effects.

What is BPC - 157 (generic for BPC - 157®)?

Peptides are short chains of amino acids, the building blocks of proteins, that play essential roles in various biological processes. We offer a range of peptides specifically designed to address different health concerns, such as weight loss, inflammation, and overall wellness. These peptides work by targeting specific areas in the body, promoting various beneficial effects.

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Peptides are short chains of amino acids, the building blocks of proteins, that play essential roles in various biological processes. We offer a range of peptides specifically designed to address different health concerns, such as weight loss, inflammation, and overall wellness.

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